Overdoses Involving Xylazine Mixed with Fentanyl: Clinical and Public Health Implications

The fully captioned video and edited transcript will be posted within the next few days.

“Please note special time of this COCA Call.”

This COCA Call will be held on Friday, March 27, 2020

This COCA Call will be held on Friday, March 27, 2020


The non-opioid drug xylazine has been found in the U.S. illegal drug supply and is associated with overdose deaths from fentanyl. Xylazine is not approved for use in people and can cause sedation and other adverse health effects. During this COCA Call, presenters will discuss the epidemiology of overdoses involving xylazine mixed with fentanyl, the current understanding of health risks related to these overdoses, and acute treatment strategies. Presenters will also review the state of laboratory testing, outline potential harm reduction activities, and provide an example of an ongoing public health and clinical partnership to mitigate harms from xylazine mixed with fentanyl.


Josh Schier, MD, MPH
CAPT, U.S. Public Health Service
Senior Medical Officer, Health Systems and Research Branch
Division of Overdose Prevention
National Center for Injury Prevention and Control
Centers for Disease Control and Prevention

Lewis Nelson, MD
Chair, Department of Emergency Medicine
Director, Division of Medical Toxicology and Addiction Medicine
Rutgers New Jersey Medical School

Rachel S. Wightman, MD
Associate Professor Emergency Medicine and Epidemiology
Alpert Medical School of Brown University
Consultant Medical Director, Rhode Island Department of Health

Call Details

Thursday, February 29, 2024
2:00 PM – 3:00 PM ET

Webinar Link:

Webinar ID: 160 603 4857

Passcode: 432103

+1 669 254 5252, or, +1 646 828 7666

One-tap mobile:

International numbers

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Call Details

Tuesday, July 26, 2022,
2:00 PM – 3:00 PM ET

Webinar Link:

Passcode: 143543

Dial In:
US: +1 669 254 5252  or +1 646 828 7666  or +1 551 285 1373  or +1 669 216 1590

International numbers

One-tap mobile:
US: +16692545252,,1615119188#,,,,*143543#  or +16468287666,,1615119188#,,,,*143543#

Webinar ID: 161 511 9188

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